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    郎美東教授
    發布人: 發布時間: 2014-09-24 作者: 訪問次數: 20356

    姓名
    郎美東
    性別
    出生年月
    1966.8
    職稱
    教授
    所屬
    教研室

    教育部醫用生物材料工程研究中心

    辦公室
    地點

    徐匯校區實驗一樓302室

    E-mail
    mdlang@ecust.edu.cn
    聯系電話
    021-64253916
    招生專業
    材料科學與工程,材料工程bob电竞竞猜,高分子化學與物理

    郎美東

                   
    主要經歷與簡歷:                           
    1987年畢業于浙江師范大學化學系;1993年獲吉林大學理學碩士;1996年獲吉林大學理學博士;1996年8月至1998年6月為中國科學院化學研究所博士后;1998年6月至2000年7月為美國康奈爾大學 (Cornell University) 博士后研究員 (Postdoc Research Fellow);2000年7月至2002年5月為美國密執根大學 (University of Michigan) 研究員 (Research Fellow);2002年7月復旦大學副教授bob电竞竞猜;2003年7月華東理工大學教授、博士生導師bob电竞竞猜。獲美國杜邦全球科學和工程獎(DuPont Science & Engineering Grant),入選國家教育部新世紀優秀人才、上海市曙光學者。
    主要研究方向: 
    功能高分子材料bob电竞竞猜、藥物控釋材料bob电竞竞猜、組織工程材料、水凝膠、藥物晶型、藥物劑型等。
    主要社會兼職:
    功能高分子學報副主編bob电竞竞猜、華東理工大學學報編委、中國晶體學會藥物晶體學專業委員會常務委員、上海市醫藥專業高級專業職稱學科組專家、上海市化學建材行業協會常務理事會理事bob电竞竞猜。
                    
    ?
    科研基本概況
    已在J Am Chem Soc, Adv Funct Mater, J Pharm Sci, Biomacromoleculs, J Mater Chem, J Polym Sci,中國科學B等國內外主流學術刊物上發表論文百余篇bob电竞竞猜,被Chem Rew, Nat Chem, Adv Drug Deliver Rev, J Am Chem Soc, Angew Chem Int Edit, Drug Discov Tody, Adv Funct Mater, Chem Mater, Chem Comm等SCI論文引用2200多篇次;申請國內外專利二十多項,其中授權十多項bob电竞竞猜。在藥物晶型研究中bob电竞竞猜,提出了以聚合物材料來誘導藥物異相成核從而選擇和控制藥物晶型的思路,開辟了一條控制晶型及搜尋未知晶型的有效途徑;在生物材料領域,主要從事材料官能團化和生物活性化修飾等領域研究,部分專利成果已為美國產業界所采用,有望獲得良好的經濟效益和社會效益。
    ?
    ?
    ?

    在研項目

     

    (1). 醫用級聚碳酸酯的合成及在手術縫合線方面的應用開發,國家重點研發計劃,2016YFC1100703bob电竞竞猜,2016-07~2020-12,子課題負責人bob电竞竞猜;

    (2). 鍵合型長效抗菌保鮮包裝材料關鍵技術研發及產業化,“十二五”國家科技支撐項目“防腐保鮮新型物流包裝材料開發”(2015BAD16B05子課題(2015BAD16B05-04),2015-01~2017-12bob电竞竞猜,子課題負責人;

    (3). 3D打印橋梁用PC材料匹配性和基本配方研究,2017-09-04~2018-07-01,項目負責人bob电竞竞猜;

    (4). 3D打印橋梁噴頭設計及基本參數研究,2017-09-04~2018-07-01,項目負責人;

    (5). 景觀橋梁打印及熒光改性,2017-09-04~2018-07-01,項目負責人bob电竞竞猜;

    (6). 纖維素/PET接枝共聚物材料的制備及應用研究,2017-01-01~2019-12-31,項目負責人。

      

    代表性論文

    2017

    (1). JunZhang, Yan Xiao*, Xueli Luo, Lianlei Wen, Andreas Heise and Meidong Lang*. Schizophrenic poly(ε-caprolactone)s: synthesis, self-assembly and fluorescent decoration. Polymer Chemistry 2017, 8(21), 3261-3270.

    (2). YanXiao*, Sihuan Lang, Jing Qin, Rui Yin, Andreas Heise, Meidong Lang*. A highly stretchable bioelastomer prepared by UV curing of liquid-like poly (4-methyl-ε-caprolactone) precursors. Journal Materials Chemistry B 2017, 5(3), 595-603.

    (3). Yixing Dai, Shuo Wang,Weibin Shi*, Meidong Lang*.pH-responsive carboxymethyl chitosan-derived micelles as apatinibcarriers for effective anti-angiogenesis activity: Preparation andin vitro evaluation. Carbohydrate Polymers 2017, 176, 107-116.

    (4). Chao Wei, Yan Zhang*, Yiru Xia, Zhongchen Song, Heng Xu, and Meidong Lang*. Enhanced Bioreduction-responsive Biodegradable Diselenidε-Containing Poly(ester urethane) Nanocarriers. Biomaterials Science 2017, 5(4), 669-677.

    (5). YunlongSun, Changlin Chen, Heng Xu, Kun Lei, Guanzhe Xu, Li Zhao*, Meidong Lang*. Surface modification of silicon wafer by grafting novel zwitterionic polymers to improve its antifouling property. Applied Surface Science 2017, 419, 642-649.

    (6). Guanzhe Xu, Yan Xiao*, Liang Cheng, Runhua Zhou, Heng Xu, Yimin Chai, Meidong Lang*. Synthesis and rheological investigation of self-healable deferoxamine grafted alginate hydrogel. Journal of Polymer Science, Part B: Polymer Physics 2017, 55(11), 856-865.

    (7). Yan Xiao*,Jianqiang Wang, Jun Zhang, Andreas Heise, Meidong Lang*. Synthesis and gelation of copolypept(o)ides with random and block structure. Biopolymers 2017, 107(10), 1-9.

    (8). Yunlong Sun,Changlin Chen, Heng Xu, Kun Lei, Guanzhe Xu, Li Zhao*, Meidong Lang*. Synthesis and Antibacterial Performance of Functional Organic-norganic Silica Nanocomposites Based on Novel Zwitterionic Polymer. Journal of Inorganic and Organometallic Polymers and Materials 2017, 27(5), 1351-1364.

    (9). Yan Zhang*, YingXu, Chao Wei, Yuanying Zhang, Liu Yang, Zhongchen Song, Meidong Lang*. Diselenide-containing poly(ε-caprolactone)-based thermo-responsive hydrogels with oxidation and reduction-triggered degradation. Materials Today Chemistry 2017, 4, 172-179.

    2016

    (10). Yan Zhang*, Xiaolin Du, Dan Hu, Jing Zhang, Yan Zhou, Guoquan Min, and Meidong Lang*. Combined Chemical Groups and Topographical Nanopattern on the Poly(epsilon-Caprolactone) Surface for Regulating Human Foreskin Fibroblasts Behavior. ACS Applied Materials & Interfaces 2016, 8(12), 7720-7728.

    (11). Yongjun Li*, Zukai Jian, Meidong Lang, Chunming Zhang, Xiaoyu Huang*. Covalently Functionalized Graphene by Radical Polymers for Graphene-Based High-Performance Cathode Materials. ACS Applied Materials & Interfaces 2016, 8(27), 17352-17359.

    (12). Jun Zhang, Yan Xiao*, Heng Xu, Chen Zhou, Meidong Lang*. Synthesis of well-defined carboxyl poly(ε-caprolactone) by fine-tuning the protection group. Polymer Chemistry 2016, 7(28), 4630-4637.

    (13). Chao Wei, Yan Zhang*, Heng Xu, Ying Xu, Yue Xu, Meidong Lang*. Well-defined labile diselenide-centered poly(ε-caprolactone)-based micelles for activated intracellular drug release. Journal of Materials Chemistry B 2016, 4(29), 5059-5067.

    (14). Min Chen, Lei Xu, Yan Zhou, Yan Zhang, Meidong Lang, Zhaoyang Ye*, WenSong Tan*. Poly(ε-caprolactone)-based substrates bearing pendant small chemical groups as a platform for systemic investigation of chondrogenesis. Cell Proliferation 2016, 49(4), 512-522.

    (15). Yan Zhang*, Miao Wang, Jinhai Ye, Meidong Lang*. Pendant Groups Fine-tuning Thermal Gelation of Poly(ε-caprolactone)-b-Poly(ethylene glycol)-b-Poly(ε-caprolactone) Aqueous Solution. Journal of Polymer Science, Part A: Polymer Chemistry 2016, 54(16), 2571-2581.

    (16). Vanminh Le, Meidong Lang, Weibin Shi, Jianwen Liu. A collagen-based multicellular tumor spheroid model for evaluation of the efficiency of nanoparticle drug delivery. Artificial Cells Nanomedicine and Biotechnology 2016, 44(2), 540-544.

    (17). Xiaofei Ma, Yan Xiao*, Heng Xu, Kun Lei, Meidong Lang*, Preparation, degradation and in vitro release of ciprofloxacin-eluting ureteral stents for potential antibacterial application. Materials Science and Engineering C 2016, 66, 92-99.

    (18). Guanzhe Xu, Liang Cheng, Qintong Zhang, Yunlong Sun, Changlin Chen, Yimin Chai, Meidong Lang*. In situ thioled alginate hydrogel: instant formation and its application in hemostasis. Journal of Biomaterials Applications 2016, 31(5), 721-729.

    2015

    (19). Hong Liu, Yan Xiao*, Heng Xu, Yebin Guan, Jun Zhang, Meidong Lang*. Synthetic polypeptides with varied hydrogen bonding between side groups. Chemical Communication 2015, 51, 10174-10177.

    (20). Zhengzhen Du, Yan Zhang,* Heng Xu, Meidong Lang*. Functionalized Pluronic-b-poly(ε-caprolactone)based nanocarriers of paclitaxel: solubilization, antiproliferative efficacy and in vivo pharmaceutic kinetics. Journal of Materials Chemistry B 2015, 3, 3685-3694.

    (21). Min Chen, Yi Zhang, Yan Zhou, Yan Zhang, Meidong Lang, Zhaoyang Ye*, Wen-Song Tan*. Pendant small functional groups on poly(ε-caprolactone) substrate modulate adhesion, proliferation and differentiation of human mesenchymal stem cells. Colloids and Surfaces B: Biointerfaces2015, 134, 322-331.

    (22). Vanminh Le, Jingjing Wang, Ming Yuan, Thelong Nguyen, Guifang Yin,Yuanhong Zheng, Weibin Shi, Meidong Lang, Leiming Xu*, Jianwen Liu*. An investigation of antitumor efficiency of novel sustained and targeted 5-fluorouracil nanoparticles. European Journal of Medicinal Chemistry 2015, 92, 882-889.

    (23). Yu Xia, Kai Zhu, Hao Lai, Meidong Lang, Yan Xiao, Sheng Lian, Changfa Guo*, Chunsheng Wang. Enhanced infarct myocardium repair mediated by thermosensitive copolymer hydrogel-based stem cell transplantation. Experimental Biology and Medicine2015, 240(5), 593-600.

    (24). Zhengzhen Du,Yan Zhang*, Meidong Lang*. Synthesis of functionalized Pluronic-b-poly(ε-caprolactone) and the comparative study of their pendant groups on the cellular internalization behavior. Journal of Materials Science: Materials in Medicine 2015, 26(4), 171(1-12).

    (25). 杜征臻,張琰*,葉金海,徐衡,郎美東*.聚己內酯-紫杉醇高分子前藥的合成及性能研究.化學學報 2015, 73(4), 349-356.

    2014

    (26). QingchunZhang, Ke Tan, Yan Zhang, Zhaoyang Ye*, WenSong Tan, Meidong Lang*. Insitucontrolledrelease of rhBMP-2 in gelatin-coated 3Dporous poly(ε-caprolactone) scaffolds for homogeneous bone tissue formation. Biomacromolecules 2014,15(1),84-94.

    (27). Yan Zhang,*Jinhong Li, Zhengzhen Du, Meidong Lang*. Synthesis and pH-responsiveassembly ofmethoxypoly(ethylene glycol)-b-poly(ε-caprolactone) with pendant carboxyl groups. Journal of Polymer Science, Part A: Polymer Chemistry 2014, 52(2), 188-199.

    (28). Yan Xiao*, Ming Yuan, Jun Zhang, Meidong Lang*. Functional poly(ε-caprolactone) based materials: preparation, self-assembly and application in drug delivery. Current Topics in Medicinal Chemistry 2014, 14, 781-818.

    (29). Chunhua Gu,Vanminh Le, Meidong Lang*, Jianwen Liu*. Preparation of polysaccharide derivates chitosan-graft-poly(ε-caprolactone) amphiphilic copolymer micelles for 5-Fluorouracil drug delivery. Colloids and Surfaces B: Biointerfaces2014,116 745-750.

    (30). Weibin Shi,Vanminh Le*, Chunhua Gu, Yuanhong Zheng, Meidong Lang, Yanhua Lu, Jianwen Liu*. Overcoming multidrug mesistance in 2D and 3D multure models by controlled drug chitosan-graft poly(ε-caprolactone)-based nanoparticles. Journal of Pharmaceutical Sciences 2014, 103, 1064-1074.

    (31). Weibin Shi, Chunhua Gu, Han Jiang, Mengru Zhang, Meidong Lang*. Effects of amphiphilic chitosan-g-poly(ε-caprolactone) polymer additive on paclitaxel release from modified drug-eluting stents. Materials Science and Engineering, C 2014, 45, 502-509.

    (32). Yan Zhang*, Yi Zhang, Min Chen, Yan Zhou, Meidong Lang*. Galactosylated poly(ε-caprolactone) membrane promoted liver-specific functions of HepG2 cells in vitro. Materials Science and Engineering, C 2014, 41, 52-58.

    (33). Yutong Fu, Xinyu Xia, Yan Zhang*, Jinhai Ye, Meidong Lang*. pH-responsive star-shaped functionalized poly(ethylene glycol)-b-poly(ε-caprolactone) with amino groups. Colloid and Polymer Science 2014, 292(9), 2071-2082.

    (34). Chunhu Gu, Huan Zhang, Meidong Lang*. Fabrication and Characterization of Silver Nanoparticles in Chitosan-g-poly(ε-caprolactone) Micelles. Applied Surface Science 2014, 301, 273-279.

    (35). MingYuan, Yan Xiao*, Vanminh Le, Chao Wei, Yutong Fu, Jianwen Liu and Meidong Lang*. Micelle controlled release of 5-fluorouracil: follow the guideline for good polymer-drug compatibility. Colloids and Surfaces A Physicochem Eng Aspects 2014, 457, 116-124.

    (36). Yan Xiao, Sihuan Lang, Yan Wang, Meidong Lang*. Effect of surface grafted hydroxyapatite on the improved particle dispersion and mechanical property of hydroxyapatite/poly(ε-caprolactone) scaffold. Current Nanoscience2014, 10, 855-862.

    (37). Xi Zhang, Yan Xiao, Meidong Lang*. Hydrogen bonding interaction induced complexation of mPEG-b-PAA and star PDMAEMA-b-poly(HEMA-g-PCL) hybridmicelles in water. Journal of Macromolecular Science, Part A: Pure and Applied Chemistry 2014, 51, 63-75.

    2013

    (38). Chunhua Gu, Huiyan Gu, Meidong Lang*. Molecular simulation to predict miscibility and phasese paration behavior of chitosan/ poly(ε-caprolactone) binary blends: a comparison with experiments. Macromoleculatr Theory and Simulation2013, 22(7), 377-384.

    (39). Yan Zhang*, Li Zhao, Min Chen, Meidong Lang*. Synthesis and properties of Pluronic-based penta block copolymers with pendant amino groups. ColloidandPolymer Science. 2013, 291(7), 1563-1571.

    (40). Tianyi Wu, Qingchun Zhang, Weiping Ren, Xiang Yi, Zubin Zhou, Xiaochun Peng, Xiaowei Yu,* Meidong Lang*. Controlled release of gentamicin from gelatin/genipinre inforced beta-tricalcium phosphate scaffold for the treatment of osteomyelitis. Journal of Materials Chemistry B 2013, 1(26), 3304-3313.

    (41). Yan Zhang*, Zhaojun Wang, Weimin Zhou, Guoquan Min, Meidong Lang*. Cationic poly(ε-caprolactone) surface functionalized mesoporoussilica nanoparticles and their application in drug delivery. Applied Surface Science 2013, 276,769-775.

    (42). Qingchun Zhang, Yan Zhang*, Meidong Lang*. Mild method for the agglomeration of dispersed polycaprolactone microspheres via a genipin-crosslinked gelatin hydrogel. Journalof Applied Polymer Science 2013,129(2),689-698.

    (43). Xi Zhang, Yan Xiao and Meidong Lang*. Synthesis and degradation behavior of miktoarm poly(ε-caprolactone)2-b-poly(L-lactone)2 microspheres. Polymer Journal 2013, 45(4), 420-426.

    (44). Qingchun Zhang, Houyong Luo, Yan Zhang, Yan Zhou, Zhaoyang Ye*, Wensong Tan, Meidong Lang*. Fabrication of three-dimensional poly(ε-caprolactone) scaffolds with hierarchical pore structures for tissue engineering. Materials Science and Engineering C 2013, 33(4), 2094-2103.

    (45). Chunhua Gu, Weibin Shi, Meidong Lang*. Enhanced mechanical property of chitosan via blending with functional poly(ε-caprolactone). Journal of Polymer Science Part B: Polymer Physics 2013, 51(8), 659-667.

    (46). Yan Zhang*, Jianjing Liu, Yutong Fu, Ke Tan, Zhaoyang Ye, Meidong Lang*. Self-assembly of polyion complex nanocarriers from ammonium glycyrrhizinate and monomethoxy poly(ethylene glycol)-b-poly(γ-amino-ε-caprolactone). Journal of Materials Chemistry B 2013, 1(11), 1614-1621.

    (47). Qingqing Bian, Yan Xiao*, Chen Zhou, Meidong Lang*. Synthesis, self-assembly, and pH-responsive behavior of (photo-crosslinked) star amphiphilic triblock copolymer. Journal of Colloid and Interface Science 2013, 392, 141-150.

    2012

    (48). Sheng Lian, Yan Xiao*, Qingqing Bian, Yu Xia, Changfa Guo, Shenguo Wang, Meidong Lang*. Injectable hydrogel as stem cell scaffolds from the thermosensitive terpolymer of NIPAAm/AAc/HEMAPCL. International Journal of Nanomedicine 2012,7 4893-4905.

    (49). Qingchun Zhang, Ke Tan, Zhaoyang Ye, Yan Zhang*, Wensong Tan, Meidong Lang*. Preparation of open porous polycaprolactone microspheres and their applications aseffective cell carriers in hydrogel system. Materials Science and Engineering C 2012, 32(8), 2589-2595.

    (50). Xiujuan Huang, Yan Xiao*, and Meidong Lang*. Synthesis ofstar-shaped PCL-based copolymers viaone-pot ATRP and their self-assembly behavior in aqueous solution. MacromolecularResearch 2012,20(6), 597-604.

    (51). Qingqing Bian, Yan Xiao*, Meidong Lang*.Thermoresponsive biotinylated star amphiphilic block copolymer: synthesis, self-assembly, andspecific recognition. Polymer 2012, 53(8), 1684-1693.

    (52). Xi Zhang, Yan Xiao, Weifeng Dai, Meidong Lang*. Synthesis and self-assembly behaviors of four-arm star blockcopolymers poly((ε-caprolactone) -b- poly(2-(diethylamino) ethyl methacrylate)) in aqueous solution. Journal of Macromolecular Science, Part A: Pure and Applied Chemistry2012 49(2), 124-130.

    (53). Yi Zhang, Yan Zhang*, Min Chen, Jinliang Yan, Zhaoyang Ye, Yan Zhou, Wensong Tan and Meidong Lang*. Surface properties of amino-functionalized poly(ε-caprolactone) membranes and the improvement of human mesenchymal stem cell behavior. Journal of Colloid and Interface Science 2012,368, 64-69.

    (54). Qingqing Bian, Yan Xiao* and Meidong Lang*. R-RAFT approach for the polymerization of N-isopropylacrylamide with a star poly(ε-caprolactone) core. Journal of Polymer Science Part A: Polymer Chemistry 2012, 50(3), 571-580.

    (55). Xiujuan Huang, Yan Xiao*, Wei Zhang, Meidong Lang*. In-situ formation of silver nanoparticles stabilized by amphiphilic star-shaped copolymer and their catalytic application. Applied Surface Science 2012, 258(7), 2655-2660.

    (56). Xiujuan Huang, Yan Xiao*, Meidong Lang*. Micelles/sodium-alginate composite gel beads: a new matrix for oral drug delivery of indomethacin. Carbohydrate Polymers2012,87(1), 790-798.

    (57). Cuizhen Li, Chunhua Gu, Yan Zhang, Meidong Lang*. Synthesis and self-assembly of pH-responsiveamphiphilic poly(ε-caprolactone)-block-poly(acrylic acid) copolymer. Polymer Bulletin 2012, 68(1),69-83.

    2011

    (58). Cui Wang, Yan Xiao*, Andreas Heise, Meidong Lang*. Organometallic and enzymatic catalysis for ring opening copolymerization of ε-caprolactone and 4-methyl-ε-caprolactone. Journal of Polymer Science Part A: Polymer Chemistry 2011, 49, 5293-5300.

    (59). Yan Deng, Yongjun Li, Jing Dai, Meidong Lang, Xiaoyu Huang*. Functionalization of graphene oxide towards thermo-sensitive nanocomposites via moderate in situ SET-LRP. Journal of Polymer Science Part A: Polymer Chemistry 2011, 49(22), 4747-4755.

    (60). Xiujuan Huang, Yan Xiao*, Meidong Lang*. Self-assembly of pH-sensitive mixed micelles based on linear and star copolymers for drug delivery. Journal of Colloid and Interface Science 2011, 364, 92-99.

    (61). Jinliang Yan, Zhaoyang Ye*, Min Chen, Zhanzhan Liu, Yan Xiao, Yan Zhang, Yan Zhou, Wensong Tan, Meidong Lang*. Fine tuning micellarcore-forming block of poly(ethylene glycol)-block-poly(ε-caprolactone) amphiphilic copolymers based on chemical modification for the solubilization and delivery of doxorubicin. Biomacromolecules 2011, 12(7), 2562-2572.

    (62). Yan Wang, Yan Xiao*, Xiujuan Huang, Meidong Lang*. Preparation and characterization of poly(methyl methacrylate) grafted hydroxyapatite nanoparticles. Journal of Colloid and Interface Science 2011, 360(2), 415-421.

    (63). Jinliang Yan, Zhaoyang Ye*, Houyong Luo, Min Chen, Yan Zhou, Yan Xiao, Yan Zhang, Wensong Tan, Meidong Lang*. Synthesis, characterization and bioconjugation of functional mPEG-b-PCL amphiphilic block copolymers: towards multi-functional micelles. Polymer Chemistry 2011, 2(6), 1331-1340.

    (64). Jianjing Liu, Yan Zhang*, Jinliang Yan, Meidong Lang*. Synthesis and solution properties of pH responsive methoxy poly(ethylene glycol)-b-p(γ-amino-ε-caprolactone). Journal of Materials Chemistry 2011, 21(18), 6677-6682.

    (65). Yan Wang, Xi Zhang, Jinliang Yan, Yan Xiao, Meidong Lang*. Surface modification of hydroxyapatite with poly(methyl methacrylate) via surface-initiated ATRP. Applied Surface Science 2011, 257(14): 6233-6238.

    (66). Yue Zeng, Yan Zhang*, Meidong Lang*. Synthesis and characterization of poly(ε-caprolactone-co-δ-valerolactone) with pendant carboxylic functional groups. Chinese Journal of Chemistry 2011, 29(2), 343-350.

    (67). Yan Deng, Yongjun Li, Jing Dai, Meidong Lang, Xiaoyu Huang*. An efficient way to functionalize graphene sheets with presynthesized polymer via ATNRC chemistry. Journal of Polymer Science Part A: Polymer Chemistry 2011 49(7), 1582-1590.

    (68). Yan Zhang, Jiashi Li, Meidong Lang*, Xiaolin Tang, Lei Li*, Xizhong Shen. Folate-functionalized nanoparticles for controlled 5-Fluorouracil delivery. Journal of Colloid and Interface Science 2011, 354(1), 202-209.

    (69). Xiujuan Huang, Yan Xiao, Meidong Lang*. Synthesis and self-assembly behavior of six-armed blockcopolymers with pH- and thermo-responsive properties. Macromolecular Research 2011, 19(2), 113-121.

    2010年之前

    (70). Yueying He, Yan Zhang, Yan Xiao, Meidong Lang*. Dual-response nanocarrier based on graft copolymers with hydrazone bond linkages forimproved drug delivery. Colloids and Surfaces B: Biointerfaces 2010, 80(2), 145-154.

    (71). Yan Wang, Jing Dai, Qingchun Zhang, Yan Xiao, Meidong Lang*. Improved mechanical properties of hydroxyapatite/poly(ε-caprolactone)scaffolds by surface modification of hydroxyapatite. Applied Surface Science 2010,256(20), 6107-6112.

    (72). Weifeng Dai, Zhengzhen Du, Yan Zhang, Minliang Ru, Meidong Lang*. The pH-induced thermosensitive amphiphilic graft copolymermicelles for drug delivery. Journal of Materials Science: Materials in Medicine 2010, 21(6),1881-1890.

    (73). Jinliang Yan, Yi Zhang, Yan Xiao, Yan Zhang, Meidong Lang*. Novel poly(ε-caprolactone)s bearing amino groups: Synthesis,characterization and biotinylation. Reactive & Functional Polymers 2010, 70(7), 400-407.

    (74). Yueying He, Yan Zhang, Chunhua Gu, Weifeng Dai, Meidong Lang*. Micellar carrier based on methoxy poly(ethylene glycol)-block-poly(ε-caprolactone) block copolymers bearing ketone groups on the polyester block for doxorubicin delivery. Journal of Materials Science: Materials in Medicine 2010, 21(2),567-574.

    (75). Jiashi Li,Yan Zhang, Jie Chen,Chaohua Wang, and Meidong Lang*. Preparation, characterization and drug release behaviorof 5-Fluorouracil loaded carboxylic poly(ε-caprolactone) nanoparticles. Journal of Macromolecular Science Part A: Pure and Applied Chemistry 2009, 46(11), 1103-1113.

    (76). Weifeng Dai, Jiayun Zhu, Aoyu Shangguan, Meidong Lang*. Synthesis, characterization and degradability of the comb-type poly(4-hydroxyl-ε-caprolactone-co-ε-caprolactone)-g-poly(L-lactide). European Polymer Journal 2009, 45(6), 1659-1667.

    (77). Wenru Zhao, Meidong Lang, Yongsheng Li, Liang Li and Jianlin Shi*. Fabrication of uniform hollow mesoporous silica spheres and ellipsoids oftunable size through a facile hard-templating route. Journal of Material Chemistry 2009, 19(18), 2778–2783.

    (78). Wenru Zhao, Hangrong Chen, Yongsheng Li, Liang Li, Meidong Lang, and Jianlin Shi*. Uniform rattle-type hollow magnetic mesoporous spheres as drug delivery carriers and their sustained-release property. Advanced Functional Materials 2008, 18(18), 2780–2788.

    (79). Weifeng Dai, Hui Huang, Zhengzhen Du, Meidong Lang*. Synthesis, characterization and degradability of the novel aliphatic polyester bearing pendant N-isopropylamidefunctional groups. Polymer Degradation and Stability 2008, 93(12), 2089-2095.

    (80). Weifeng Dai, Chaohua Wang, Xi Zhang, Jinming Zhang and Meidong Lang*. Michael addition reactions of cyclanones with acrylamides: Producing 2-carbamoylethyl derivatives or ene-lactams. Science in China Series B Chemistry 2008, 51(11), 1044-1050.

    (81). Adam L Grzesiak, Meidong Lang, Kibum Kim, Adam J Matzger*. Comparison of thefouranhydrouspolymorphs of carbamazepine and thecrystalstructure ofform I. Journal of Pharmaceutical Sciences 2003, 92(11),2260-2271.

    (82). Meidong Lang, Jeff W Kampf, Adam J Matzger*. Form IV ofcarbamazepine. Journal of Pharmaceutical Sciences 2002, 91(4), 1186-1190.

    (83). Meidong Lang, Chih-Chang Chu*. Functionalized multiarm poly(ε-caprolactone)s: synthesis, structure alanalysis and network formation. Journal of Applied Polymer Science 2002, 86, 2296-2306.

    (84). Meidong Lang, Renee P Wong, Chih-Chang Chu*. Synthesis andstructuralanalysis offunctionalized poly(epsilon-caprolactone)- based three-arm star polymers. Journal of Polymer Science. Part A, Polymer Chemistry 2002, 40(8), 1127-1141.

    (85). CP Price, A LGrzesiak, Meidong Lang, A J Matzger*. Polymorphism ofnabumetone. Crystal Growth&Design 2002, 2(6), 501-503.

    (86). Meidong Lang, Adam L Grzesiak, Adam J Matzger*.The use of polymer heteronuclei for crystalline polymorph selection. Journal of the American Chemical Society 2002, 124(50), 14834-14835.

    (87). Meidong Lang, Chih-Chang Chu*, Synthesis and chemical structural analysis of nitroxyl-radical-incorporated poly(acrylic acid/lactide/ε-caprolactone) copolymers. Journal of Polymer Science, Part A: Polymer Chemistry 2001, 39(24), 4214-4226.

    (88). Meidong Lang, Jianzhong Bei, Shenguo Wang*. Synthesis and characterization of polycaprolactone/poly(ethylene oxide)/polylactide tri-component copolymers. JournalofBiomaterials Science, Polymer Edition 1999, 10(4), 501-512.

    (89). Meidong Lang*,Guo Zhang, Xinfang Chen, Na Feng, Shuhua Li. Poly(ethylene glycol)-block-poly(butyl acrylate). II. Characterization and properties. Journal Applied Polymer Science 1998, 70(8), 1427-1436.

    (90). Meidong Lang*,Guo Zhang, Na Feng, Shuhua Li, Xinfang Chen. Poly(ethyleneglycol)-block-poly (butyl acrylate). I.Synthesis. Journal of Applied Polymer Science 1997, 65(9), 1667-1674.

    (91). Meidong Lang*,Guo Zhang, Na Feng, Xinfang Chen. The synthesis of poly(ethylene oxide)-block-poly(butyl acrylate). Chemistry Research of Chinese University 1997, 13(1), 77-82.

    (92). Zhudi Zhao*, HuaiYang, Meidong Lang, Xinfang Chen. The effects of radiation oncrystal transformations of poly(vinylidene fluoride). Chemistry Research of Chinese University 1994, 10(3), 197-201.

    專利

    授權專利

    (1). 郎美東,顧春華. 改性聚(ε-己內酯)藥物洗脫支架的方法. 專利號:ZL 201210355642.4,授權公告日:20150218.

    (2). 張琰,王召君,郎美東. (γ-氨基-ε-己內酯)/空心介孔二氧化硅雜化材料. 專利號:ZL 201310020608.6bob电竞竞猜,授權公告日:20150211.

    (3). 郎美東,肖艷,卜宇. 聚谷氨酸衍生物及其水凝膠和制備方法. 專利號:ZL 201310055049.2bob电竞竞猜,授權公告日:20140820.

    (4). 郎美東,張清淳. 天然高分子修飾的介孔聚己內酯及其用途. 專利號:ZL 201110365908.9,授權公告日:20140723.

    (5). 郎美東,嚴金良. ε-己內酯衍生物及其聚合物. 專利號:ZL 200910050425.2,授權公告日:20140219.

    (6). 郎美東,張清淳. 介孔結構的聚己內酯及其制備方法和用途. 專利號:ZL 201110065665.7, 授權公告日:2013717.

    (7). 張琰,劉建靜,郎美東,嚴金良. 專利號:ZL 201110212768.1bob电竞竞猜,授權公告日:2012125.

    (8). 郎美東,李家詩,張琰. 葉酸鍵接的ε-己內酯類聚合物.專利號:ZL 200910053384.2, 授權公告日:2011330.

    (9). 郎美東,戴煒楓. 二環烯基內酰胺的制備方法. 專利號:ZL 200610025762.2, 授權公告日:200835.

    (10). 郎美東,顧青,何耀bob电竞竞猜bob电竞竞猜,黃維. 生物降解性醫用高分子材料的內酯單體及其制備方法. 專利號:ZL 200410016814.0, 授權公告日:200614.

    (11). Meidong Lang, Chih-Chang Chu. Biodegradable copolymers linked to segment with a plurality of functional groups, 加拿大專利號: CA 2,440,394, 公開日: 2011-10-4.

    (12). Meidong Lang, Chih-Chang Chu. Biodegradable copolymers linked to segment with a plurality of functional groups, Patent No:US6830747 B2, Pub Date:2004-12-14.

    (13). Meidong Lang and Chih-Chang Chu. Biodegradable Polyhydric Alcohol Ester, Patent No:US 6,592,895 B2, Date of Patent: Jul. 15, 2003. Filed: Jul. 15, 2002. Appl. No.: 10/194,945.

    (14). Adam Matzger, Meidong Lang and Kibum Kim. Systems and Methods for the Generation of Crystalline Polymorphs, Patent No: US 7,429,238 B2, Date of Patent: Sep. 30, 2008. Filed: Oct. 11, 2002. Appl.No: US20020269190 20021011

    (15). Meidong Lang, Chih-Chang Chu. Biodegradable Polyhydric Alcohol Esters, Patent Number: WO 03/011212 A2, Publication date: Feb. 13, 2003. Filed: Jul. 15, 2002. Appl. No.: PCT/US02/19816.

    (16). Meidong Lang, Chih-Chang Chu. Biodegradable Copolymers Linked of Functional Groups, Patent Number: WO 02/090417 A1, Publication date: Nov. 14, 2002. Filed Mar. 20, 2002. Appl. No.: PCT/US02/06642.

    公開專利

    (1). 郎美東bob电竞竞猜,張俊,肖艷. ε-己內酯衍生物及其制備方法和應用. 公開號:CN 107298673 A,公開日:2017.10.27.

    (2). 郎美東,孫云龍,陳昌林. 一種兩性離子共聚物薄膜材料及其制備方法. 公開號:CN 107033274 A,公開日:2017.08.11.

    (3). 郎美東bob电竞竞猜bob电竞竞猜,雷昆. 一種阻燃保溫用雙組份改性三聚氰胺甲醛泡沫板的制備方法. 公開號:CN 106967275 A, 公開日:2017.07.21.

    (4). 郎美東,張麗,侯佳bob电竞竞猜,梁文城. 聚對苯二甲酸?1,4?環己烷二甲醇酯薄膜的制備方法及用途. 公開號:CN 106947071 A, 公開日:2017.07.14.

    (5). 郎美東bob电竞竞猜,孫云龍. 4-乙烯基吡啶磺酸鹽/二氧化硅納米雜化抗菌材料及其制備方法. 公開號:CN 106916402 A, 公開日:2017.07.04.

    (6). 郎美東bob电竞竞猜,魏超,張琰,許悅,閆炳坤,杜征臻. 一種制備雜環碳酸酯的方法. 公開號:CN 106905292 A, 公開日:2017.06.30.

    (7). 郎美東,馬曉飛. 用于腫瘤定向治療的輸尿管支架及制備方法. 公開號:CN 106890368 A, 公開日:2017.06.27.

    (8). 張修銀bob电竞竞猜,郎美東,黃爭美,王申春,馬曉飛,韓智慧. 米諾環素緩釋制劑. 公開號:CN 106822066 A, 公開日:2017.06.13.

    (9). 張修銀bob电竞竞猜,郎美東,黃爭美,王申春,馬曉飛,韓智慧. 可降解生物薄膜、其制備方法以及硝唑類緩釋制劑. 公開號:CN 106589337 A, 公開日:2017.04.26.

    (10). 白富棟,郎美東bob电竞竞猜,沙陳杰,方向晨bob电竞竞猜,李政. 一種纖維素及其衍生物的接枝共聚物及其合成方法. 公開號:CN 106146855 A, 公開日:216.11.23.

    (11). 肖艷,郎思睆bob电竞竞猜,郎美東. 一種提高聚己內酯基生物彈性體力學性能的方法. 公開號:CN 105936667 A, 公開日:2016.09.14.

    (12). 張琰,胥瑩,魏超,郎美東. 一種開環聚合制備含硒可降解聚合物的方法及其在水凝膠的應用. 公開號:CN 105732990 A, 公開日:2016.07.06.

    (13). 張琰,王淼bob电竞竞猜,郎美東,傅雨桐. 一種可注射溫敏性物理水凝膠及其制備方法. 公開號:CN 105396137 A, 公開日:2016.03.16.

    (14). 郎美東,許冠哲,徐衡. 改性海藻酸鈉及其用途. 公開號:CN 105273105 A,公開日:2016.01.27.

      

    聯系方式

     

    華東理工大學 材料科學與工程學院 實驗一樓302室

    電話:021-64253916, 64253432. 傳真:021-64253916

    E-mail:mdlang@ecust.edu.cn

    通訊地址:上海市梅隴路130號391信箱. 郵編:200237

     

     

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